Publikationen
2023
The role of human lipoproteins for hepatitis C virus persistence. Current Opinion in Virology (2023).
Vieyres G, Pietschmann T.
2022
The Railmap of Type I Interferon Induction: Subcellular Network Plan and How Viruses Can Change Tracks. Cells (2022).
Weber L., Vieyres G.
2021
Lipid Droplet Contact Sites in Health and Disease. Trends in Cell Biology (2021).
Herker E, Vieyres G, Beller M, Krahmer N, Bohnert M.PicPreview and PicSummary: Two Timesaving Plugins for the Fluorescence Microscopist. Cells (2021).
Vieyres G.Initial HCV infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro- and anti-viral elements. Journal of Virology (2021).
Tegtmeyer B, Vieyres G , Todt D, Lauber C, Ginkel C, Engelmann M, Herrmann M, Pfaller CK , Vondran FWR, Broering R, Vafadarnejad E, Saliba A-E, Puff C, Baumgärtner W, Miskey C, Ivics Z, Steinmann E, Pietschmann T, Brown RJP.
2020
Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice. Science Advances (2020).
Brown RJP, Tegtmeyer B, Sheldon J, Khera T, Anggakusuma, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran FWR, Krey T, Ströh LJ, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr AW, McClure CP, Randall G, Baktash Y, Ploss A, Thi VLD, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice CM, Pietschmann T.Controlled functional zonation of hepatocytes in vitro by engineering of Wnt signalling. ACS Synthetic Biology (2020).
Wahlicht T, Vieyres G, Bruns SA, Meumann N, Büning H, Hauser H, Schmitz I, Pietschmann T, Wirth D.The ATGL lipase cooperates with ABHD5 to mobilize lipids for HCV assembly and lipoprotein production. PLoS Pathogens (2020).
Vieyres G, Reichert I, Carpentier C, Vondran FW, Pietschmann T.C19orf66 is an interferon-induced inhibitor of HCV replication that restricts formation of the viral replication organelle. Journal of Hepatology (2020).
Kinast V, Plociennikowska A, Anggakusuma, Bracht T, Todt D, Brown RJ, Boldanova T, Zhang Y, Brueggemann Y, Friesland M, Engelmann M, Vieyres G, Broering R, Vondran FWR, Heim MH, Sitek B, Bartenschlager R, Pietschmann T, Steinmann E.Tracking hepatitis C virus interactions with the hepatic lipid metabolism – A hitchhiker´s guide to solve remaining translational research challenges in hepatitis C. Chapter 66 ofThe Liver – Biology and Pathobiology, 6th edition. Edited by Irwin Arias, Harvey Alter, James Boyer, David Cohen, Snorri Torgeirsson, David Shafritz, and Allan Wolkoff (2020).
Vieyres G, Pietschmann T.
2019
Identification of Keratin 23 as a Hepatitis C Virus-Induced Host Factor in the Human Liver. Cells (2019).
Kinast V, Leber SL, Brown RJP, Vieyres G, Behrendt P, Eßbach C, Strnad P, Vondran FWR, Cornberg M, Wex C, Pietschmann T, Haybaeck J, Todt D, Steinmann E.HCV Pit Stop at the Lipid Droplet: Refuel Lipids and Put on a Lipoprotein Coat before Exit. Cells (2019).
Vieyres G, Pietschmann T.
2018
The small compound inhibitor K22 displays broad antiviral activity against different members of the family Flaviviridae and offers potential as pan-viral inhibitor. Antimicrobial Agents and Chemotherapy (2018).
García-Nicolás O, V'kovski P, Vielle NJ, Ebert N, Züst R, Portmann J, Stalder H, Gaschen V, Vieyres G, Stoffel M, Schweizer M, Summerfield A, Engler O, Pietschmann T, Todt D, Alves MP, Thiel V, Pfaender S.
2016
cGAS-mediated innate immunity spreads intercellularly through HIV-1 Env-induced membrane fusion sites. Cell Host Microbe (2016).
Xu S, Ducroux A, Ponnurangam A, Vieyres G, Franz S, Müsken M, Zillinger T, Malassa A, Ewald E, Hornung V, Barchet W, Häussler S, Pietschmann T, Goffinet C.Hepaciviral NS3/4A proteases interfere with MAVS signalling of their cognate animal hosts and also with human MAVS: implications for zoonotic transmission. Journal of Virology (2016).
Anggakusuma, Brown RJ, Banda D, Todt D, Vieyres G, Steinmann E, Pietschmann T.ABHD5/CGI-58, the Chanarin-Dorfman syndrome protein, mobilises lipid stores for hepatitis C virus production. PLoS Pathogens (2016). Selected by the Editors-in-chief as the week featured research, for a press release and as image cover for the month issue.
Vieyres G, Welsch K, Gerold G, Gentzsch J, Kahl S, Vondran FW, Kaderali L, Pietschmann T.Ion channel function and cross-species determinants in viral assembly of nonprimate hepacivirus p7. Journal of Virology (2016).
Walter S, Bollenbach A, Doerrbecker J, Pfaender S, Brown RJ, Vieyres G, Scott C, Foster R, Kumar A, Zitzmann6 N, Griffin S, Penin F, Pietschmann T, Steinmann E.Antiviral activity of different interferon (sub-) types against hepatitis E virus replication. Antimicrobial Agents and Chemotherapy (2016).
Todt D, Francois C, Anggakusuma, Behrendt P, Engelmann M, Knegendorf L, Vieyres G, Wedemeyer H, Hartmann R, Pietschmann T, Duverlie G, Steinmann E.
2015
Several human liver cell expressed apolipoproteins complement HCV virus production with varying efficacy conferring differential specific infectivity to released viruses. PLoS One (2015).
Hueging K, Weller R, Doepke M, Vieyres G, Todt D, Wölk B, Vondran FW, Geffers R, Lauber C, Kaderali L, Penin F, Pietschmann T.Transcriptome analysis reveals a classical interferon signature induced by IFNλ4 in human primary cells. Genes & Immunity (2015).
Lauber C, Vieyres G, Terczyńska-Dyla E, Anggakusuma, Dijkman R, Gad HH, Akhtar H, Geffers R, Vondran FW, Thiel V, Kaderali L, Pietschmann T, Hartmann R.
2014
Role of the hypervariable region 1 (HVR1) for the interplay of hepatitis C virus with entry factors and lipoproteins. Journal of Virology (2014).
Bankwitz D, Vieyres G, Hueging K, Bitzegeio J, Doepke M, Chhatwal P, Haid S, Catanese MT, Zeisel MB, Nicosia A, Baumert TF, Kaderali L, Pietschmann T.Apolipoprotein E co-determines tissue-tropism of hepatitis C virus and it is crucial for viral cell-to-cell transmission by contributing to a post-envelopment step of assembly. Journal of Virology (2014).
Hueging K, Doepke M, Vieyres G, Bankwitz D, Frentzen A, Doerrbecker J, Gumz F, Haid S, Wölk B, Kaderali L, Pietschmann T.Incorporation of hepatitis C virus E1 and E2 glycoproteins: the keystones on a peculiar virion. Viruses (2014).
Vieyres G, Dubuisson J, Pietschmann T.
2013
Interferon lambda 4 signals via the IFNλ receptor to regulate antiviral activity against HCV and coronaviruses. The EMBO Journal (2013).
Hamming OJ, Terczyńska-Dyla E, Vieyres G, Dijkman R, Jørgensen SE, Akhtar H, Siupka P, Pietschmann T, Thiel V, Hartmann R.Hepatitis C virus p7 is critical for capsid assembly and envelopment.PLoS Pathogens (2013).
Gentzsch J, Brohm C, Steinmann E, Friesland M, Menzel N, Vieyres G, Perin PM, Frentzen A, Kaderali L, Pietschmann T.Subcellular localization and function of an epitope-tagged p7 viroporin in hepatitis C virus-producing cells. Journal of Virology (2013).
Vieyres G, Brohm C, Friesland M, Gentzsch J, Wölk B, Roingeard P, Steinmann E, Pietschmann T.Entry and replication of recombinant hepatitis C viruses in cell culture.Methods (2013).
Vieyres G, Pietschmann T.
2011
Characterization of antibody-mediated neutralization directed against hypervariable region 1 of hepatitis C virus E2 glycoprotein. Journal of General Virology (2011).
Vieyres G, Dubuisson J, Patel AH.
2010
Characterization of the envelope glycoproteins associated with infectious hepatitis C virus. Journal of Virology (2010).Featured in JVI spotlights.
Vieyres G, Thomas X, Descamps V, Duverlie G, Patel AH, Dubuisson J.Envelope protein N-linked glycans on authentic hepatitis C virus are important for secretion, viral entry and protection against neutralization. Journal of Virology (2010).
Helle F, Vieyres G, Elkrief L, Popescu CI, Castelain S, Duverlie G, Dubuisson J.
2009
Rapid synchronization of hepatitis C virus infection by magnetic adsorption. Journal of Virological Methods (2009).
Vieyres G, Angus AG, Haberstroh A, Baumert TF, Dubuisson J, Patel AH.
2007
HCV requires a tight junction-associated protein for cell entry (review). Future Virology (2007).
Witteveldt J, Vieyres G, Patel AH.